Allergy can occur after the first injection, however, such a reaction is rare. As a rule, allergies are detected after 4 weeks of use.
It should be noted that the reaction can have varying degrees of severity. The development of Quincke's edema is not excluded.
Reactions can be divided according to the nature of their occurrence:
Immediate type - manifests itself 15-30 minutes after the injection, manifests itself as a reaction at the injection site in the form of a rash. slow type. It manifests itself in the form of the formation of subcutaneous infiltrates, manifests itself 20-35 hours after the administration of insulin.