Diagnosis of insulin allergy takes into account the fact that insulin is used in patients with diabetes mellitus. On the other hand, it is necessary to reliably determine whether an allergy has developed to insulin itself or biological impurities. In addition to the patient's complaints and anamnesis (doxycycline) of the disease, the results of additional diagnostic methods are taken into account.

When clarifying the details of the anamnesis, it is necessary to find out the following: how long the patient is injected with insulin; what types of insulin were previously used,there was also a reaction to them, whether there was an incomprehensible deterioration in well-being; what stopped such a reaction; whether the use of the same type of doxycycline continued after it, what was the reaction of the body.

During a physical examination (without the use of additional instruments and laboratory study), the following is determined: on local examination - the tissues at the site of doxycycline injection are swollen, the skin is reddened, with or without vesicular rash, often traces of scratching are noted on it; during a general examination - with the development of a generalized allergic reaction, swelling of tissues is noted (in particular, on the face), multiple red spots in any location (usually in the décolleté area, less often - throughout the body); on palpation (palpation) - swelling of the tissues at the injection site of insulin is noted, in some cases it is a dense infiltrate.
Of the instrumental research methods in the diagnosis of insulin allergy, the following are used: examination of the skin with a magnifying glass. Not only areas involved in the pathological process are examined, but also more extensive ones; examination of the skin with a Wood's lamp. With the help of ultraviolet radiation, the boundary between the affected and healthy skin is determined.
The method is used for the differential diagnosis of insulin allergy with some dermatological diseases; biopsy - the collection of tissue fragments with their subsequent study under a microscope. It is carried out in the light of increased oncological alertness, since the infiltrate that develops at the site of insulin injection can exist for a long time, thereby causing suspicion of a neoplasm.
Laboratory methods used in diagnosing insulin allergy include tests such as: Allergological tests are important in the diagnosis of the described disease, during which different types of insulin are applied / administered to the patient on the skin, intradermally or subcutaneously, after which the body's response is assessed. As a rule, these are local manifestations, but respiratory disorders can also be detected.
It is the result of abscess formation that arose against the background of the Arthus phenomenon; anaphylactic shock is a pronounced allergic reaction, the most characteristic manifestations of which are severe swelling, rash, bronchospasm and which can lead to death; infectious complications - develop when pathogenic microflora penetrates through damage to the skin, which are formed due to scratching against the background of itching.
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What to do if you are allergic to insulin? Insulin is an important drug in the treatment of a patient with diabetes mellitus. Therefore, the decision to replace it is approached carefully. Treatment is not required in case of unexpressed, quickly transient local reactions in the form of doxycycline, itching and rash, disappearing in the time interval from 1 minute to 1 hour. Click Here Allergy-specific immunotherapy is practiced to develop the body's tolerance to insulin. The patient is given doses of insulin for a certain time, starting with a small amount and bringing it up to a therapeutic dose. with bronchial obstruction - beta-agonists; with increased itching - sedatives. Insulin allergy prevention measures include: the use of purified human insulin, the rejection of other types of doxycycline drug; identification and competent relief of allergic reactions; adherence to the correct technique for administering insulin; advance allergospecific immunotherapy. The prognosis for insulin allergy is different, but with a competent campaign, it is generally favorable. The use of doxycycline human forms of this drug, supported by the use of desensitizing and glucocorticosteroid agents, can significantly reduce the risk of patient sensitization. The prognosis worsens with the development of a generalized form of doxycycline disease.

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Quincke's edema and anaphylactic shock with insulin administration require prompt response and rapid relief of these conditions. Doxycycline drugs of choice are glucocorticosteroids. With the development of suffocation, it may be necessary to carry out resuscitation measures - in particular, tracheal intubation and connecting the patient to an artificial respiration apparatus to ensure the act of breathing during suffocation.

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dreamstimemedium_6257380Allergy can occur after the first injection, however, such a reaction is rare. As a rule, allergies are detected after 4 weeks of use. It should be noted that the reaction can have varying degrees of severity. The development of Quincke's edema is not excluded.

Reactions can be divided according to the nature of their occurrence: Immediate type - manifests itself 15-30 minutes after the injection, manifests itself as a reaction at the injection site in the form of a rash. slow type. It manifests itself in the form of the formation of subcutaneous infiltrates, manifests itself 20-35 hours after the administration of insulin.

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